• 文献标题:   Cell Proliferation Tracking Using Graphene Sensor Arrays
  • 文献类型:   Article
  • 作  者:   DALY R, KUMAR S, LUKACS G, LEE K, WEIDLICH A, HEGNER M, DUESBERG GS
  • 作者关键词:  
  • 出版物名称:   JOURNAL OF SENSORS
  • ISSN:   1687-725X EI 1687-7268
  • 通讯作者地址:   Univ Dublin Trinity Coll
  • 被引频次:   8
  • DOI:   10.1155/2012/219485
  • 出版年:   2012

▎ 摘  要

The development of a novel label-free graphene sensor array is presented. Detection is based on modification of graphene FET devices and specifically monitoring the change in composition of the nutritive components in culturing medium. Microdispensing of Escherichia coli in medium shows feasibility of accurate positioning over each sensor while still allowing cell proliferation. Graphene FET device fabrication, sample dosing, and initial electrical characterisation have been completed and show a promising approach to reducing the sample size and lead time for diagnostic and drug development protocols through a label-free and reusable sensor array fabricated with standard and scalable microfabrication technologies.