• 文献标题:   Paramagnetic Properties of Metal-Free Boron-Doped Graphene Quantum Dots and Their Application for Safe Magnetic Resonance Imaging
  • 文献类型:   Article
  • 作  者:   WANG H, REVIA R, WANG K, KANT RJ, MU QX, GAI Z, HONG KL, ZHANG MQ
  • 作者关键词:  
  • 出版物名称:   ADVANCED MATERIALS
  • ISSN:   0935-9648 EI 1521-4095
  • 通讯作者地址:   Univ Washington
  • 被引频次:   19
  • DOI:   10.1002/adma.201605416
  • 出版年:   2017

▎ 摘  要

A boron-doped graphene quantum dot (B-GQD) as a metal-free multimodal contrast agent (CA) for safe magnetic resonance imaging and fluorescence imaging is reported. In vivo T1-weighted magnetic resonance images show that B-GQDs induce significant contrast enhancement on the heart, liver, spleen, and kidney, and sustain for more than 1 h, about 10 times longer than Gd-based CAs currently used in clinic.