▎ 摘　　要

Rice blast is a destructive rice disease that is rapidlyspreadby the drift of Magnaporthe oryzae spores.Conidial attachment to the rice leaf surface is the most crucial stepin the rapid spread of rice blast. Therefore, blocking the chanceof contact between spores and the rice leaf surface is extremely vitalfor controlling rice blast. In this study, based on the strong affinitybetween the lectin protein-ConA and M. oryzae spores, we successfully constructed ConA-loaded PEGylated grapheneoxide (GO-PEG-ConA) as targeted nanopesticide carriers to load epoxiconazole(EPX) against M. oryzae. The ConA loadingcapacity of the GO-PEG-EPX-ConA nanocarrier was 14.7% by the sodiumdodecyl sulfate-polyacrylamide gel electrophoresis assay. TheGO-PEG-ConA nanocarrier could obviously inhibit the germination of M. oryzae spores by 41.7% and showed 2.4-fold higherinhibitory activity than the inhibition ratio (17.4%) of GO-PEG nanocarriers,which was mainly due to the higher affinity between the GO-PEG-ConAnanocarrier and M. oryzae spores. Moreover,the greenhouse experiment indicated that the GO-PEG-EPX-ConA nanopesticidecould significantly reduce rice blast lesions in rice seedlings, fundamentallysettling the transmission of rice blast. Therefore, GO-PEG-ConA couldbe a targeted nanopesticide carrier to realize precise release ofpesticides, which would offer an important reference value for improvingpesticide utilization efficiency.