• 文献标题:   Heteroatom engineered graphene-based electrochemical assay for the quantification of high-risk abused drug oxytocin in edibles and biological samples
  • 文献类型:   Article
  • 作  者:   THOMAS R, BALACHANDRAN M
  • 作者关键词:   oxytocin, electrooxidation, heteroatom, co doping, synergistic effect
  • 出版物名称:   FOOD CHEMISTRY
  • ISSN:   0308-8146 EI 1873-7072
  • 通讯作者地址:  
  • 被引频次:   2
  • DOI:   10.1016/j.foodchem.2022.134106 EA SEP 2022
  • 出版年:   2023

▎ 摘  要

The naive detection of scheduled H drug oxytocin is a vital requisite, owing to its deleterious impact on societal affluence prompted by unconstrained usage. Therefore, a reliable, cost-effective, and quick-to-respond analytic technique for this drug is in ample demand. In this work, we report electrochemical detection of oxytocin employing novel nitrogen, phosphorus co-doped coke-derived graphene (NPG) modified electrode. The electrooxidation behavior of oxytocin was investigated on the NPG modified electrode by square wave stripping voltammetry (SWSV) in 0.1 M phosphate buffer of pH 7. The oxidation peak current was linear in two ranges, spanning from 0.1 nM to 10 nM and 15 nM to 95 nM. The limit of detection at the NPG electrode was calculated to be 40 pM. The practical application of developed sensor for the determination of oxytocin was examined in edible products and body fluids, hence signifying the possibility of having real-time surveillance over its misusage.