▎ 摘　　要

Abuse of midecamycin (MD) has posed a series of side effects to human health. Therefore, the detection of MD is critical to optimal treatment and avoidance of toxic concentrations. Till now, several carbon materials such as multi-walled carbon nanotube (MWCNT) and graphene modified electrodes were developed for MD determination. However, in relative with these one or two-dimensional (1D or 2D) carbon materials, 3D structural materials display more excellent characteristics, such as higher specific surface, better electrical conductivity and more desirable electrocatalytic activity. Inspired by this, in this study, a novel electrochemical MD sensing platform has been proposed based on 3D N-doped graphene aerogels (NGAs) material. Electrochemical results indicate that NGAs modified electrode exhibited prominent sensing performances toward MD, which is mainly ascribed to the fact that the 3D porous structure provides multiple electron path and unhindered substance diffusion. Besides, the large specific surface area ensures rich active sites for the catalytic reaction of MD. Furthermore, N doping can effectively adjust their bandgap and electron density. Under the optimized conditions, the as-prepared sensor could detect MD concentrations down to 0.01 mu M (S/N= 3) with the linear range of 0.03-21 mu M. The sensor exhibited good performances with high sensitivity, selectivity, and long-term stability.