▎ 摘　　要

The Poly(3,4-ethylenedioxythiophene) graphene (PEDOT. rGO) composite film was prepared by one step pulse potentiostatic method, based on the pi-pi* interaction and the polymerization reaction of hydrogen bond between the graphene (rGO) and the aromatic ring of 3,4-ethylenedioxythiophene (EDOT) monomer. Then the nickel nanoparticles (NiNPs) were electrodeposited on composite film to obtain a composite film. modified glassy carbon electrode (NiNPs/PEDOT. rGO/GCE). The catalytic performance of NiNPs/PEDOT-rGO/GCE towards the oxidation of glucose was studied by electrochemical method. The experimental results showed that the NiNPs/PEDOT-rGO/GCE could be used as a nonenzyematic sensor for detection of glucose. This method had high stability, good selectivity, wide linear range (2 mu mol/L-58 mmol/L) and low detection limit (0. 7 mu mol/L), realizing the rapid and sensitive detection of glucose.