• 文献标题:   A label-free DNA reduced graphene oxide-based fluorescent sensor for highly sensitive and selective detection of hemin
  • 文献类型:   Article
  • 作  者:   SHI Y, HUANG WT, LUO HQ, LI NB
  • 作者关键词:  
  • 出版物名称:   CHEMICAL COMMUNICATIONS
  • ISSN:   1359-7345
  • 通讯作者地址:   Southwest Univ
  • 被引频次:   96
  • DOI:   10.1039/c0cc05518b
  • 出版年:   2011

▎ 摘  要

G-quadruplex structure aptamer (PS2.M) can capture acridine orange (AO) from reduced graphene oxide (rGO). When the AO-PS2.M/rGO mixture is incubated with hemin, the specific binding of hemin with PS2.M results in a release of AO from PS2.M and return of AO back to rGO. Based on the quenching of fluorescence, the target hemin was detected sensitively and selectively, giving a detection limit of 50 nM.