• 文献标题:   Polystyrene@graphene oxide-Fe3O4 as a novel and magnetically recyclable nanocatalyst for the efficient multi-component synthesis of spiro indene derivatives
  • 文献类型:   Article
  • 作  者:   HOJATI SF, AMIRI A, MAHAMED M
  • 作者关键词:   spiro indene derivative, onepot synthesi, polystyrene@gofe3o4 nanocomposite, multicomponent reaction
  • 出版物名称:   RESEARCH ON CHEMICAL INTERMEDIATES
  • ISSN:   0922-6168 EI 1568-5675
  • 通讯作者地址:   Hakim Sabzevari Univ
  • 被引频次:   0
  • DOI:   10.1007/s11164-019-04021-w EA OCT 2019
  • 出版年:   2020

▎ 摘  要

Polystyrene (PS)-coated magnetic graphene oxide (GO-Fe3O4) nanocomposite has been prepared and characterized by FT-IR, TEM and VSM techniques, and its catalytic activity has been evaluated in the multi-component synthesis of two series of indene derivatives. The three-component condensation of ninhydrin/isatin, malononitrile and active methylene-containing compounds and also the four-component condensation of ninhydrin, o-phenylenediamines, malononitrile and active methylene-containing compounds were satisfactorily performed in the presence of PS@GO-Fe3O4 magnetic nanocomposite, and corresponding 2 '-aminospiro[indene-2,4 '-pyran]-3 '-carbonitriles, 2 '-aminospiro[indoline-3, 4 '-pyran]-3 '-carbonitriles and 2 '-aminospiro[indeno[1,2-b]quinoxaline-11,4 '-pyrane]-3 '-carbonitriles were obtained in good-to-excellent yields, respectively. Very shorter reaction times than the reported methods, easy workup procedure and easy separation and reusability of the catalyst are noteworthy advantages of the current method.