• 文献标题:   Synthesis of nitrogen-doped reduced graphene oxide loading with Au-Ag bimetallic nanoparticles for electrochemical detection of daunorubicin
  • 文献类型:   Article
  • 作  者:   KONG FY, YAO L, LI RF, LI HY, WANG ZX, LV WX, WANG W
  • 作者关键词:   nitrogendoped reduced graphene oxide, auag bimetallic nanoparticle, modified electrode, daunorubicin, voltammetric detection
  • 出版物名称:   JOURNAL OF ALLOYS COMPOUNDS
  • ISSN:   0925-8388 EI 1873-4669
  • 通讯作者地址:   Yancheng Inst Technol
  • 被引频次:   13
  • DOI:   10.1016/j.jallcom.2019.04.276
  • 出版年:   2019

▎ 摘  要

Nitrogen-doped reduced graphene oxide loading with Au-Ag bimetallic nanoparticles (NG-Au-Ag) was synthesized by a facile two-step strategy. The successful formation of NG-Au-Ag nanocomposites were confirmed by transmission electron microscopy (TEM), Raman spectroscopy, X-ray photoelectron spectroscopy (XPS) and X-ray diffraction (XRD) analysis. Furthermore, NG-Au-Ag nanocomposites were modified onto the electrode surface for the voltammetric detection of daunorubicin (DNR). The results showed that the NG-Au-Ag modified electrode expressed high electrocatalytic activity toward the redox of DNR, allowed detection of DNR with wide linear range (0.01 mu g mL(-1) to 15 mu g mL(-1)) and low detection limit (3 ng mL(-1)). The modified electrode also exhibited satisfactory performance for the detection of DNR in human serum samples. (C) 2019 Elsevier B.V. All rights reserved.