• 文献标题:   Concentration-dependent magnetic hyperthermic response of manganese ferrite-loaded ultrasmall graphene oxide nanocomposites
  • 文献类型:   Article
  • 作  者:   PENG E, DING J, XUE JM
  • 作者关键词:  
  • 出版物名称:   NEW JOURNAL OF CHEMISTRY
  • ISSN:   1144-0546 EI 1369-9261
  • 通讯作者地址:   Natl Univ Singapore
  • 被引频次:   15
  • DOI:   10.1039/c3nj01555f
  • 出版年:   2014

▎ 摘  要

Water soluble and biocompatible similar to 18 nm manganese-doped ferrite (MnxFe1-x)Fe2O4 decorated ultrasmall graphene oxide (GO) nanocomposites were synthesized. Ultrasmall nanocomposites were fabricated with a hydrodynamic size of 50.6 +/- 0.3 nm, approximately similar to 80 nm lateral dimension and similar to 20 nm thickness (from AFM analysis), indicating a sheet-like structure with only a few nanoparticles attached. The concentration-dependent magnetic hyperthermic response of such nanocomposites under an alternating magnetic field (AMF) and very dilute conditions (<0.3 mg ml(-1)) was also investigated. The field-dependent specific absorption rate (SAR) values of the nanocomposites were found to have increased by approximately two-fold when their concentration was reduced by a factor of 3. Such nanocomposites also exhibited excellent colloidal stability as well as suitable biocompatibility (up to 2 mM iron concentration) with NIH/3T3 fibroblast cells.