▎ 摘　　要

Simple hydrothermal route was developed for synthesis of NiMnO3 in the presence of graphene quantum dot. The structure and morphological aspect of nano-hybrid were approved using FE-SEM, XRD and FT-IR. Then, these nano-particles were chosen as a modifier in carbon paste electrode, which produces noticeable catalytic effect for electro-oxidation of dobutamine. The oxidation mechanism of the drug was also studied using cyclic voltammetry. After variable optimization, a linear regression function was found in the range of 0.08-40.0 mu M with the detection limit of 0.02 mu M between the concentration of dobutamine and its anodic signal. The utility of the modified electrode was assessed by measuring the concentration of dobutamine in serum samples.