• 文献标题:   Synthesis and Characterization of Graphene like Carbon Nanosheet: Interaction with some Drug Molecules and Anticancer Activity
  • 文献类型:   Article
  • 作  者:   CHATTOPADHYAY AP, MANDAL P, SARKAR R, SAMADDER A, KHUDABUKHSH AR, YADAV P, SARKAR K
  • 作者关键词:   apoptosi, carbon nanosheet, drug binding, graphenelike, reduced graphene oxide
  • 出版物名称:   CHEMISTRYSELECT
  • ISSN:   2365-6549
  • 通讯作者地址:   Univ Kalyani
  • 被引频次:   1
  • DOI:   10.1002/slct.201601443
  • 出版年:   2017

▎ 摘  要

Graphene-like carbon nano-sheets are prepared from dextrin, with cetyltrimethyl ammonium bromide (CTAB) as stabiliser, by the action of concentrated sulfuric acid. Oxidation of such sheets produce graphene oxide (GO) like material. These are characterized in the usual manner and their photophysical properties are explored. Binding of certain drug molecules with carbon nano-sheet is investigated fluorimetrically. Finally, action of carbon nano-sheets on normal and cancer cell lines revealed that the sheets have no effect on normal cells, but induce apoptosis on cancer cells. Also, these carbon nano-sheets behave very similar to reduced graphene oxide platelets.