• 文献标题:   Reactive Graphene Oxide Nanosheets: A Versatile Platform for the Fabrication of Graphene Oxide-Biomolecule/Polymer Nanohybrids
  • 文献类型:   Article
  • 作  者:   XU LQ, ZHANG B, CHEN Y, NEOH KG, KANG ET, FU GD
  • 作者关键词:   biocompatibility, electrical switching, graphene oxide, nanocomposite, reactive pentafluorophenyl ester
  • 出版物名称:   MACROMOLECULAR RAPID COMMUNICATIONS
  • ISSN:   1022-1336 EI 1521-3927
  • 通讯作者地址:   E China Univ Sci Technol
  • 被引频次:   20
  • DOI:   10.1002/marc.201200635
  • 出版年:   2013

▎ 摘  要

Graphene oxide (GO) nanosheets can be functionalized with reactive pentafluorophenyl ester via esterification of the carboxylic groups. The resulting reactive GO nanosheets provide a versatile platform for grafting of amino-containing polymers or biomolecules via ester-amine coupling. Coupling of poly[(9,9-dioctylfluorene)-alt-(4-amino-phenylcarbazole)] (PFCz-NH2), amino-terminated hyperbranched polyglycerol (HPG-NH2), and lysozyme (Lyz) was illustrated. The Al/GO-g-PFCz/ITO sandwich thin-film device exhibits bistable electrical switching and rewritable memory effects. The GO-g-Lyz nanohybrids exhibit high bactericidal efficacy against S. aureus and E. coli, while the GO-g-HPG nanohybrids exhibit reduced cytotoxicity toward 3T3 fibroblasts.