• 文献标题:   Rapid Sequencing of Individual DNA Molecules in Graphene Nanogaps
  • 文献类型:   Article
  • 作  者:   POSTMA HWC
  • 作者关键词:   dna, sequencing, graphene
  • 出版物名称:   NANO LETTERS
  • ISSN:   1530-6984 EI 1530-6992
  • 通讯作者地址:   Calif State Univ Northridge
  • 被引频次:   259
  • DOI:   10.1021/nl9029237
  • 出版年:   2010

▎ 摘  要

I propose a technique for reading the base sequence of a single DNA molecule using a graphene nanogap to read the DNA's transverse conductance. Because graphene is a single atom thick, single-base resolution of the conductance is readily obtained. The nonlinear current-voltage characteristic is used to determine the base type independent of nanogap-width variations that cause the current to change by 5 orders of magnitude. The expected sequencing error rate is 0% up to a nanogap width of 1.6 nm.