▎ 摘　　要

A highly flexible and selective electrochemical sensor based on a Pt-Au nanoparticles (Pt-AuNPs) modified laser-induced graphene (LIG)/Polydimethylsiloxane (PDMS) electrode is presented for the detection of dopamine (DA). The Pt-AuNPs exhibited high electrocatalytic activity in response to the oxidation of DA, and the peak current of DA detected by the Pt-AuNPs/LIG/PDMS electrode linearly increased with DA concentration. The fabricated sensor also exhibited an excellent sensitivity of approximately 865.80 mu A/mM cm(-2) and a detection limit of 75 nM in a neutral solution. In addition, it showed high selectivity for interfering compounds such as uric acid (UA) and ascorbic acid (AA). Clearly defined current peaks, with a separation of approximately 0.11 V, were observed for DA and UA. Finally, DA was successfully detected in human urine. (C) 2019 Elsevier Ltd. All rights reserved.