• 文献标题:   Infrared Laser-Induced Graphene Sensor for Tyrosine Detection
  • 文献类型:   Article
  • 作  者:   MATIAS TA, ROCHA RG, FARIA LV, RICHTER EM, MUNOZ RAA
  • 作者关键词:   biological fluid, differential pulse voltammetry, disposable sensor, laserscribed graphene, polyimide sheet
  • 出版物名称:   CHEMELECTROCHEM
  • ISSN:   2196-0216
  • 通讯作者地址:  
  • 被引频次:   1
  • DOI:   10.1002/celc.202200339 EA JUN 2022
  • 出版年:   2022

▎ 摘  要

In this work, we demonstrate that laser-induced graphene (LIG) electrodes produced by a single-step infrared irradiation on a commercially available polyimide sheet work as portable platforms for the electrochemical detection of tyrosine (Tyr). The LIG surface was characterized by Raman and scanning electron microscopy, which confirmed the formation of graphene with a highly porous structure. The sensor associated with differential-pulse voltammetry provided the determination of Tyr with a linear range between 5 and 30 mu mol L-1, a limit of detection (LOD) of 1.5 mu mol L-1, precision of 6.2 % (n=10), and a satisfying selectivity towards interfering species found in biological media (e. g., dopamine, urea, and both ascorbic and uric acids). Artificial urine samples spiked with different amounts were analyzed by the proposed sensor and recovery values between 107 and 114 % were obtained. Opposite to many works reported in the literature, this platform did not require costly and time-consuming surface modification processes, being an alternative feasible for other applications of clinical/medical interest. One LIG electrode sensor is produced in 140 s without chemical waste generation.