• 文献标题:   Graphene quantum dots (GQDs)-based nanomaterials for improving photodynamic therapy in cancer treatment
  • 文献类型:   Review
  • 作  者:   FAN HY, YU XH, WANG K, YIN YJ, TANG YJ, TANG YL, LIANG XH
  • 作者关键词:   graphene quantum dot, photodynamic therapy, nanomaterial, drug delivery, cancer therapy
  • 出版物名称:   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
  • ISSN:   0223-5234 EI 1768-3254
  • 通讯作者地址:   Sichuan Univ
  • 被引频次:   9
  • DOI:   10.1016/j.ejmech.2019.111620
  • 出版年:   2019

▎ 摘  要

Graphene quantum dots (GQDs) as novel nanomaterials, have received significant interest in the field of biomedical applications. It is worth noting that a large amount of research is devoted to GQDs-based nanocomposites for cancer treatment, especially for photodynamic therapy (PDT), in that they can act not only as more favorable photosensitizers (PSs) but also nanoplatforms for delivering PSs. In this review, the biological behavior and physicochemical properties of GQDs for PDT are described in detail, and the application of GQDs-based nanocomposites in improved PDT and PDT-based combination therapies is analyzed, which may provide a new strategy for designing efficient PDT systems for cancer treatment. (C) 2019 Elsevier Masson SAS. All rights reserved.