• 文献标题:   Miniaturization of self-assembled solid phase extraction based on graphene oxide/chitosan coupled with liquid chromatography for the determination of sulfonamide residues in egg and honey
  • 文献类型:   Article
  • 作  者:   LI YZ, LI ZQ, WANG WP, ZHONG SX, CHEN JR, WANG AJ
  • 作者关键词:   miniaturization of selfassembled solid phase extraction, graphene oxide/chitosan, sulfonamide residue, liquid chromatography, egg honey
  • 出版物名称:   JOURNAL OF CHROMATOGRAPHY A
  • ISSN:   0021-9673 EI 1873-3778
  • 通讯作者地址:   Zhejiang Normal Univ
  • 被引频次:   14
  • DOI:   10.1016/j.chroma.2016.04.026
  • 出版年:   2016

▎ 摘  要

The miniaturization of self-assembled solid phase extraction (m-SASPE) based on graphene oxide/chitosan (GO/CS) coupled with liquid chromatography-ultraviolet detection was developed for rapid screening of five sulfonamide residues in egg and honey. GO/CS was synthesized by solution blending method and characterized by FT-IR, X-ray diffraction (XRD) and scanning electron microscopy (SEM). Parameters that affected extraction efficiency including sample pH, amount of the GO/CS, elution solvent and rotation speed were optimized in detail. Under the optimal conditions, good linear relationships between the peak area and the concentrations of the analytes were obtained. The linear ranges were 0.01-10.00 mu gg(-1) with correlation coefficients (r) >= 0.9989. The method detection limits (MDLs) were in the range of 0.71-0.98 ng g(-1). The relative standard deviations (RSDs) of intra- and inter-day analysis were less than 3.5 and 7.1%, respectively. The proposed method was successfully applied for the analysis of sulfonamide residues in egg and honey. The average recoveries for two samples spiked at levels from 0.02 to 2.0 mu gg(-1) were in the range of 75.3-105.2% with RSDs less than 13.5%. (C) 2016 Elsevier B.V. All rights reserved.