▎ 摘　　要

The aim of this study was to describe the modification of the bioactivity of Al2O3-noble metal (Me = Ag, Au, or Pd) composite nanoparticles by the addition of graphene oxide and the formation of a RGO/Al2O3-Me nanocomposite system. The nanocomposite flakes and Al2O3-Me composite nanoparticles were widely characterized. The antibacterial effect was observed only for Al2O3-Ag composite nanoparticles and RGO/Al2O3-Ag nanocomposite flakes, while, in the case of RGO/Al2O3-Ag, a more evident antibacterial effect against Staphylococcus aureus bacteria was observed compared with Al2O3-Ag. In the case of other noble metals (Au, Pd), a slight growth-stimulating effect was revealed for particular bacterial strains.