▎ 摘 要
In this study, the first CA nanofibers were fabricated by electrospinning under optimal conditions: flow rate of 0.5 ml/h, a voltage of 20 kV, electrospinning distance of 15 cm, and an internal temperature of 25 degrees C, and humidity of 38%. The used Graphene/gold nanoparticles for CA performance improvement were examined by TGA, XRD, and SEM analysis. Then the CA/graphene-gold nanocomposite was synthesized under optimum electrospinning conditions: flow rate 3 ml/h, voltage 20 kV, electrospinning distance 15 cm, internal temperature 26. C, and humidity 36%. The SEM images revealed that the nanofibers' thicknesses of Graphene-gold NPs (CA(1)) and Chitosan (CA(2)) were 350 and 120 nm, respectively. The XRD diagrams of CA(0), CA(1) and CA(2) revealed the peaks at 2 degrees, 8 degrees, and 21. with Miller indices of (001) and (110) are related to CA (CA(0)), which proves its presence in other scaffolds. The FTIR analysis of samples indicated the presence of graphene-gold NPs in scaffolding CA(1) and CA(2). The CA(2) nanofibers exhibited a high-water absorption capacity of about 2500% with the water contactangle and Swelling method. The antibacterial properties of this nanocomposite were also confirmed by an antibacterial test on Staphylococcus aureus bacteria. The growth of Schwann cells on three scaffolds showed the highest growth of cells on CA(1) scaffolds.