• 文献标题:   Ornidazole-loaded graphene paper for combined antibacterial materials
  • 文献类型:   Article
  • 作  者:   QIAN WH, WANG ZL, HE DN, HUANG XY, SU JS
  • 作者关键词:   ornidazole, graphene oxide, antibacterial material
  • 出版物名称:   JOURNAL OF SAUDI CHEMICAL SOCIETY
  • ISSN:   1319-6103 EI 2212-4640
  • 通讯作者地址:   Tongji Univ
  • 被引频次:   3
  • DOI:   10.1016/j.jscs.2017.10.002
  • 出版年:   2018

▎ 摘  要

Excellent antibacterial property of graphene oxide makes it an important antibacterial material. However, in some cases, a synergistic combination of materials with different antibacterial mechanisms is desired. In this work, we developed a simple two-step protocol to prepare ornidazole (ONZ), a nitroimidazole antiprotozoal drug, loaded graphene-based paper for combined antibacterial materials. Graphene oxide (GO) and reduced graphene oxide (rGO) were used as carriers in antibacterial materials. After mixed with ONZ directly in aqueous media and filtrated under vacuum, the freestanding GO/ONZ and rGO/ONZ were peeled off from the filtrate membrane. The ONZ loading contents in the paper was determined by UV/vis spectroscopy and the surface properties were investigated by measuring their contact angle, which will have an important impact on the antibacterial effects of the papers. (C) 2017 King Saud University. Production and hosting by Elsevier B.V.