• 文献标题:   A nanohybrid composed of polyoxotungstate and graphene oxide for dispersive micro solid-phase extraction of non-steroidal anti-inflammatory drugs prior to their quantitation by HPLC
  • 文献类型:   Article
  • 作  者:   AMIRI A, MIRZAEI M, DERAKHSHANRAD S
  • 作者关键词:   polyoxometalate, carbonbased nanomaterial, poly diallyldimethylammonium chloride, sample preparation, tap water analysi, river water analysi, wastewater analysi, anion exchange polymer
  • 出版物名称:   MICROCHIMICA ACTA
  • ISSN:   0026-3672 EI 1436-5073
  • 通讯作者地址:   Hakim Sabzevari Univ
  • 被引频次:   12
  • DOI:   10.1007/s00604-019-3694-0
  • 出版年:   2019

▎ 摘  要

A nanohybrid was prepared from polyoxotungstate anion and graphene oxide (POT/GO) and characterized in terms of porosity by applying Fourier transform infrared and transmission electron microscopy. The nanohybrid was applied as a sorbent for the dispersive micro solid-phase extraction of the non-steroidal anti-inflammatory drugs (NSAIDs) ibuprofen, diclofenac, and naproxen. Different types of sorbents were compared, and the POT/GO nanohybrid was found to have the best adsorption affinity. The NSAIDs were quantified via HPLC with UV detection. Under the optimum conditions, the limits of detection (at an S/N ratio of 3) range between 0.02-0.03ng.mL(-1), and the linear response ranges extend from 0.08-200ng.mL(-1), respectively. The relative standard deviations (RSDs) for five replicates at three concentration levels (0.1, 5 and 100ng.mL(-1)) of NSAIDs ranged from 4.1 to 6.1%. The applicability of the method was confirmed by analyzing spiked real water samples, and satisfactory results were obtained, with recoveries between 95.6 and 99.6%.