• 文献标题:   3D-printed layer-by-layer electrode graphene/poly(1,8-diaminonaphthalene) incorporated with silver nanoparticles as an electrochemical sensing platform for cefepime antibiotic determination
  • 文献类型:   Article, Early Access
  • 作  者:   DO TT, VAN GIAP H, NGUYEN MTT, HOANG DT, NGUYEN HL, LE LT, TRAN LD, NGUYEN DT
  • 作者关键词:   3dprinted graphene electrode, silver nanoparticle, poly 1, 8diaminonaphthalene, cefepime antibiotic
  • 出版物名称:   COLLOID POLYMER SCIENCE
  • ISSN:   0303-402X EI 1435-1536
  • 通讯作者地址:  
  • 被引频次:   0
  • DOI:   10.1007/s00396-023-05126-w EA MAY 2023
  • 出版年:   2023

▎ 摘  要

This article presents a new electrode made with a 3D printer which is coated with a layer of graphene oxide and poly(1,8-diaminonaphthalene) combined with silver nanoparticles as an electro-catalyst for the detection of the antibiotic cefepime, an important fourth-generation cephalosporin. This nanocomposite-based 3D printing electrode showed an enhanced electrocatalytic activity toward cefepime with high sensitivity and stability in neutral pH media. The linear relationship between the height of peak current and cefepime concentration allowed the differential pulse voltammetry determination of cefepime from 0.4 to 4.0 mu M, and the limit of detection was 0.08 mu M. The proposed electrode was successfully applied for the determination of cefepime as the drug in pharmaceutical formulations sample.