▎ 摘　　要

In the present study, the optimum range of prism refractive index and better surface plasmons active metals for biosensing application are obtained on the basis of performance of the proposed SPR sensor. Proposed sensor utilizes the properties of graphene and MoS2 such as; mechanically strong, atomically thin and chemically inert coating for the protection against oxidation of SPs active metal. It is observed that the prism having moderate refractive index should be preferred and sensor having silver (Ag) has minimum full width at half maximum whereas copper (Cu) has maximum shift in resonance angle. Hence, Ag can be used for high quality and resolution whereas Cu for good sensitivity, which are protected from oxidation with the help of two dimensional MoS2 or graphene, or graphene over MoS2.