▎ 摘　　要

In this work, a reduced graphene oxide sensor associated to the batch injection analysis system with amperometric detection was investigated for the simple, fast and sensitive monitoring of sulfanilamide in lake water and synthetic biological fluid (saliva, sweat and urine) samples. The modified sensor showed a potential displacement of 170 mV and an increase in peak current of 5.5-fold for the electrochemical oxidation of sulfanilamide in comparison to the bare electrode, resulting in a highly sensitive and selective method. Besides, the developed method showed excellent analytical performance with a limit of detection of 2.30 mu mol L-1, linear range from 10 to 50 mu mol L-1, relative standard deviation below 5.6%, and recovery ranges varying from 83 to 109% for the analysis of spiked samples. In addition, the minimum sample preparation (simple dilution) combined with a high analytical frequency (130 analyses per hour) can be highlighted. Thus, the proposed method demonstrates to be a promising analytical tool for the implementation in routine analysis of clinical interest and environmental monitoring in loco.