• 文献标题:   Optimization of reduced graphene oxide production using central composite design from Pennisetum glaucum for biomedical applications
  • 文献类型:   Article
  • 作  者:   PREETHY KR, CHAMUNDEESWARI M
  • 作者关键词:   antiinflammatory, antioxidant, biogel, biofilm, biomedical application
  • 出版物名称:   BIOTECHNOLOGY APPLIED BIOCHEMISTRY
  • ISSN:   0885-4513 EI 1470-8744
  • 通讯作者地址:  
  • 被引频次:   0
  • DOI:   10.1002/bab.2397 EA AUG 2022
  • 出版年:   2023

▎ 摘  要

The current study outlines the toxicity-free green synthesis of reduced graphene oxide (GO) using Celosia argenta. The synthesized sample was characterized by UV-visible spectroscopy with a strong absorption peak at 260 nm due to redshift. The 2 theta value around 24.1 degrees by X-ray diffraction analysis and the functional groups like OH, CH2, CC, and CHO by Fourier transmission infrared spectroscopy confirmed the reduction of GO. Field emission scanning electron microscopy-energy-dispersive X-ray spectroscopy reported stacked sheets with smooth edges with an atomic ratio of carbon:oxygen (83.56:16.44). The transmission electron microscope images proved the reduction of GO by folded thin sheets with the wrinkled appearance of our sample. This novel material showed antibacterial efficiency of 51.72-70.83% for both Gram-negative and Gram-positive organisms. 89.48% of antioxidant effect and potential anti-inflammatory property with the IC50 value of 86.04% was reported. RSM study proved the optimization of maximum yield and two-way analysis of variance reported the statistical significance (p value