• 文献标题:   An Ultrasensitive Contact Lens Sensor Based On Self-Assembly Graphene For Continuous Intraocular Pressure Monitoring
  • 文献类型:   Article
  • 作  者:   LIU ZD, WANG G, YE C, SUN HY, PEI WH, WEI CR, DAI W, DOU ZQ, SUN QY, LIN CT, WANG YJ, CHEN HD, SHEN GZ
  • 作者关键词:   glaucoma, intraocular pressure, radio frequency identification, self #8208, assembly graphene, wireles
  • 出版物名称:   ADVANCED FUNCTIONAL MATERIALS
  • ISSN:   1616-301X EI 1616-3028
  • 通讯作者地址:  
  • 被引频次:   21
  • DOI:   10.1002/adfm.202010991 EA MAY 2021
  • 出版年:   2021

▎ 摘  要

Elevated intraocular pressure (IOP) is the leading cause of glaucoma. As glaucoma is an irreversible neurological eye disease, it is urgent to realize timely and accurate IOP detection for diagnostic and therapeutic purposes. Here, a contact lens sensor for continuous IOP monitoring using self-assembly graphene (SAG), is developed. The combination of face-to-face water transfer printing and micro-electromechanical systems technology can realize the batch preparation of such a sensor. The sensor has good light transmittance and temperature stability. It exhibits an ultra-high IOP sensitivity of 1.0164 mV mm Hg-1 on a silicone eye, and 3.166 mV mm Hg-1 in vitro on the porcine eye with remarkable linearity. The sensitivity of the proposed sensor is high enough to be read by a commercial radio frequency identification read-write system for continuous wireless monitoring of IOP. Furthermore, the as-prepared sensor can work as normal for 24 h in phosphate buffer saline.