• 文献标题:   Graphene Nanocomposites Based Electrochemical Sensing Platform for Simultaneous Detection of Multi-drugs
  • 文献类型:   Article
  • 作  者:   PHAM TSH, HASEGAWA S, MAHON P, GUERIN K, DUBOIS M, YU AM
  • 作者关键词:   electrochemical sensing, reduced graphene oxide, antibiotics measurement
  • 出版物名称:   ELECTROANALYSIS
  • ISSN:   1040-0397 EI 1521-4109
  • 通讯作者地址:  
  • 被引频次:   5
  • DOI:   10.1002/elan.202100485 EA NOV 2021
  • 出版年:   2022

▎ 摘  要

Three reduced graphene oxide nanocomposites were employed to achieve the simultaneous electrochemical determination of multi-drugs including acetaminophen (ACTM), carbendazim (CB) and ciprofloxacin (CFX). All nanocomposite modified electrodes showed improved current responses for three drugs. Notably cauliflower-like platinum nanoparticles decorated reduced graphene oxide modified electrode (or Pt-RGO/GCE) exhibited the best performance in terms of electrochemical stability. Using Pt-RGO/GCE, the linear detect ranges of 30-120 mu M, 25-115 mu M and 10-25 mu M, and detection limit values of 3.49, 2.96, and 1.53 mu M were achieved for ACTM, CB and CFX respectively. The electrode was further used for the successful determination of above drugs in tap and river water using differential pulse voltammetry. From the obtained results, we believe that Pt-RGO/GCE is highly promising for the fabrication of robust electrochemical sensors for simultaneously determining ACTM, CB and CFX or similar types of drugs in the future.