• 文献标题:   Carbon dots doped tungstic anhydride on graphene oxide nanopanels: A new picomolar-range creatinine selective enzymeless electrochemical sensor
  • 文献类型:   Article
  • 作  者:   PONNAIAH SK, PRAKASH P
  • 作者关键词:   nanocomposite, modified electrode, cds/wo3@go, creatinine, urine blood sample
  • 出版物名称:   MATERIALS SCIENCE ENGINEERING CMATERIALS FOR BIOLOGICAL APPLICATIONS
  • ISSN:   0928-4931 EI 1873-0191
  • 通讯作者地址:   Thiagarajar Coll
  • 被引频次:   3
  • DOI:   10.1016/j.msec.2020.111010
  • 出版年:   2020

▎ 摘  要

The measurement of renal function by important clinical parameters such as (Crt) clearance and glomerular filtration rate often goes wrong vis-a-vis the Crt level in human body. Hence, development of an accurate detection system over a wide range of Crt concentration in both blood and urine is medically essential. In this study, a new non-enzymatic electrochemical probe, carbon dots doped tungstic anhydride embedded on graphene oxide nanopanels (CDs/WO3@GO) is reported for picomolar-level Crt detection in blood and urine with a wide linear range (0.2-112.0 nM). The sensor is economical, reproducible, stable and interferents-free. The properties of CDs/WO3@GO were studied using various analytical techniques. The proposed electrochemical Crt sensor could be used as a sustainable alternative for diagnostic use.