▎ 摘　　要

Combing the merits of metals and semiconductors,with superior plasmon resonance effects and high charge mobility, 3D-nanocomposite structures consisting of graphene oxide (GO), noble metal nanostructures, and two-dimensional transition metal sulfides (2D-TMDS) are an important topic in surface-enhanced Raman scattering (SERS) research. This paper presents a novel GO/Ag NPs (silver nanoparticles)/WS2 composite SERS substrate, and electric field simulation by COMSOL software. The GO/Ag/WS2 composite substrate shows very high SERS detective sensitivity and stability to probe molecules such as rhodamine 6 g (R6G), crystal violet (CV), methylene blue (MB) and deoxyribonucleic acid (DNA). The SERS sensitivity can reach 10-12 M, the relative standard deviation (RSD) is 8.24%, and the enhancement factor (EF) is approximately 6.60 x 1010 for R6G, which promoted the implementation of the SERS technique in the area of quantitative profiling and testing.(c) 2022 Optica Publishing Group under the terms of the Optica Open Access Publishing Agreement