• 文献标题:   Screening of anti-cancer activity of reduced graphene oxide biogenically synthesized against human breast cancer MCF-7 cell lines
  • 文献类型:   Article
  • 作  者:   SMINA CS, LALITHA P, SHARMA SC, NAGABHUSHANA H
  • 作者关键词:   sonication, graphene, breast cancer, cytotoxicity, mcf7
  • 出版物名称:   APPLIED NANOSCIENCE
  • ISSN:   2190-5509 EI 2190-5517
  • 通讯作者地址:  
  • 被引频次:   9
  • DOI:   10.1007/s13204-021-01696-9 EA FEB 2021
  • 出版年:   2021

▎ 摘  要

Components derived from herbal plants have received great attention in curing several diseases including cancer. In this present study, the sonication method was employed to synthesize Acorus calamus, Terminalia bellirica, Helicteres isora and Quercus infectoria mediated RGO (reduced graphene oxide). The characterization of biosynthesized RGO was done by X-ray Diffraction (XRD), Fourier Transform Infrared spectroscopy (FTIR), Ultraviolet-Visible spectroscopy (UV-Vis), Field Emission Scanning Electron Microscopy (FESEM), etc. The absorption peaks obtained for reduced graphene oxide were at 278, 262, 268 and 263 nm for ACCARGO, TBRGO, HIRGO and QIRGO, respectively. The cytotoxicity of the prepared reduced graphene oxide was examined in opposition to human breast cancer cells, MCF-7. It is clearly evident that the RGO prepared showed significant cytotoxic activity against breast cancer cells. The RGO prepared from green route is highly efficient for the large production of RGO for biomedical applications.