▎ 摘　　要

The system CaCl2-(NH4)(2)HPO4-NH3-H2O-graphene oxide (25 degrees C) was studied by the solubility method (Tananaev's residual concentration method) and by pH measurements and was used to model in vitro the biomineralization of the main inorganic component of the bone tissue-calcium hydroxyapatite (HA) Ca-10(PO4)(6)(OH)(2)-in the presence of a nanosized modification of carbon-graphene oxide (GO). It was shown that the synthesis in the system produces hybrid composite materials (CM) of the general composition Ca-10(PO4)(6)(OH)(2) center dot xGO center dot yH(2)O, where x = 0.5, 1.0, and 2.0 and y = 7.4-7.7, which contain GO and nanocrystalline (NC) HA of the stoichiometric composition. By chemical analysis, X-ray powder diffraction analysis, IR spectroscopy, thermogravimetric analysis, and differential scanning calorimetry, the main physicochemical characteristics of the synthesis products were determined, the effect of the composition on the crystallographic parameters, sizes, and morphology of NC HA in HA/GO CM was evaluated, and the main composition-structure-dispersity-properties relationships for the synthesized HA/GO CM were analyzed.