▎ 摘 要
Nanoparticles (NP) with advanced optical or photothermal properties have been explored for potential cancer therapy applications. Gold (Au)-based nanomaterials exhibit superior photothermal properties among various Photothermal therapy (PTT) agents. NANOTORRID (R) material is superior in many ways, including it is composed of dielectric polymer polypropylene carbonate and gold, it has graphitic bands like G and D, its small size range of 20-30 nm, having tunable wavelength absorbance and need for a shorter duration of laser exposure or low material concentration to deliver desired therapeutic benefit. Here, we report a scalable single pot method to produce NANOTORRID (R) structures capable of intense heat generation within a short duration of 2 to 2.5 min of laser exposure due to multiple dielectric and gold interfaces. NANOTORRID (R) exhibits excellent photothermal properties as using 10 mu g/mL concentration can reach effective temperature (43 degrees C) within only 2.5 min by absorbing a 430 mW 808 nm laser.