▎ 摘　　要

This paper presents a method for the construction of a graphene paste electrode (GPE) from reduced graphene oxide (RGO). The GPE was successfully used for the determination of medetomidine. The influence of some experimental variables such as pH, supporting electrolyte, scan rate, and possible interferences were studied. Differential pulse voltammetric (DPV) peak currents of medetomidine increased linearly with its concentration in the range from 0.009 to 2.5 mu M. The limit of detection (LOD) and limit of quantitation (LOQ) values for the determination of medetomidine were 2.8 and 9.2nM, respectively. Also, for the first time, the electroreduction behavior of medetomidine was investigated.