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  • 文献标题:   Graphene oxide-protected DNA probes for multiplex microRNA analysis in complex biological samples based on a cyclic enzymatic amplification method
  • 文献类型:   Article
  • 作　　者:   CUI L, LIN XY, LIN NH, SONG YL, ZHU Z, CHEN X, YANG CJ
  • 作者关键词:  
  • 出版物名称:   CHEMICAL COMMUNICATIONS
  • ISSN:   1359-7345
  • 通讯作者地址:   Xiamen Univ
  • 被引频次:   160
  • DOI:   10.1039/c1cc15412e
  • 出版年:   2012

▎ 摘　　要

Based on graphene oxide-protected DNA probes, we have developed a cyclic enzymatic amplification method for sensitive miRNA detection in complex biological samples. By using the quenching nature of graphene oxide for multiple fluorophores, this method can distinguish highly similar miRNA sequences and detect them simultaneously.