▎ 摘　　要

Due to lower out-of-plane electrical conductance, black phosphorus (BP) provides a suitable host material for improving the sensitivity of biosensors. However, BP oxidizes easily, which limits practical applications. In this article, we propose a sensitivity-enhanced guided-wave surface plasmon resonance (GWSPR) biosensor based on a BP-graphene hybrid structure. This BP-graphene hybrid structure exhibits strong antioxidation properties and exceptional biomoleculetrapping capability, which improve the stability and sensitivity of GWSPR biosensors, respectively. We show that the proposed GWSPR biosensor can distinguish refractive indices in the range of 1.33-1.78 RIU (RIU is the unit of RI), and the sensitivity reaches a maximum of 148.2 degrees/RIU when the refractive index of sensing target is 1.33 RIU. The high sensitivity and broad detection range indicate that the proposed biosensor could significantly impact fields such as biological and chemical detection.