▎ 摘　　要

A reduced graphene oxide (RGO) based capacitive real time bio-sensor was presented. Suspended graphene oxide (GO) film was assembled electrophoretically between the source and drain electrodes of a transistor and then reduced by annealing in hydrogen/nitrogen forming gas to optimize the surface functional groups and conductivity. The resonance frequency of the transmission coefficient (S-21) of the transistor was observed to shift with deoxyribonucleic add (DNA)-hybridization, with a detecting limit of similar to 5 nM. The advantages of the bio-sensing approach include low-noise frequency output, solution based real time detection and capable of on-chip integration. (C) 2016 Elsevier B.V. All rights reserved.