• 文献标题:   Graphene oxide as broadband hyperthermic agent and chemo-photothermal dissolution of kidney-stone mimicking calcium oxalate crystals
  • 文献类型:   Article
  • 作  者:   CHEN HY, GHOSH S, PONNUSAMY VK, CHATTOPADHYAY S
  • 作者关键词:   photothermal therapy, graphene oxide, gold nanorod, broadband, kidney stone
  • 出版物名称:   JOURNAL OF PHOTOCHEMISTRY PHOTOBIOLOGY ACHEMISTRY
  • ISSN:   1010-6030 EI 1873-2666
  • 通讯作者地址:  
  • 被引频次:   3
  • DOI:   10.1016/j.jphotochem.2020.112917
  • 出版年:   2021

▎ 摘  要

Graphene oxide (GO) and gold nanorods (AuNRs) have been extensively evaluated for broadband (325-980 nm) photothermal (PT) heat generation and efficiency, on substrates having contrasting thermal conductivities. Infrared thermal imaging of the PT agents under broadband irradiation showed a maximum rise of local temperature of chicken kidney tissue by 16.4, and 5.7 degrees C for GO and AuNR, respectively, under similar irradiation conditions. The PT conversion efficiency, derived from the cooling curves of the dynamic PT response, was found to be exceeding 60 % for GO on chicken kidney tissue under 532, 785, and 980 nm laser irradiations. The PT effect was used to enhance the dissolution rate of the kidney stone mimicking calcium oxalate crystals in the presence of hydroxyanthraquinone (AQ) solution. Mass spectrometric experiments show that the combination of AQ and GO, when irradiated with 532 nm, could chemo-photothermally dissolve calcium oxalate by at least similar to 20 % more than when using AQ alone, or using a resistive way of elevating the solution temperature.