▎ 摘 要
In this work, electrochemically reduced graphene oxide-carbon nanotube (multi-walled) nanocomposite modified glassy carbon electrode (ErGO-CNT/GCE) has been investigated for direct electrochemical determination of nitrofurantoin (NFT), which is the prime drug used in the treatment of urinary tract infection. Surface of ErGO-CNT/GCE has shown leafy flake-like layers on the nanowire bed of CNTs, promising porous surface structure with enhanced surface area. ErGO-CNT/GCE showed high peak current along with low overpotential in sensing NFT. In differential pulse voltammetry studies, the low detection limit is 20 nM. Steady state current - time analyses carried out in buffer and serum samples resulted a low-detection-limit of 1.87 nM with the analysis time of mere 5 s. Practical application of the fabricated sensor for NFT determination in serum samples has been demonstrated.