• 文献标题:   In-situ synthesis of reduced graphene oxide/silver nanoparticles (rGO/AgNPs) nanocomposites for high loading capacity of acetylsalicylic acid
  • 文献类型:   Article
  • 作  者:   HANDAYANI M, SUWAJI BI, ASIH GIN, KUSUMANINGSIH T, KUSUMASTUTI Y, ROCHMADI, ANSHORI I
  • 作者关键词:   graphene oxide, hummer method, insitu synthesi, reduced graphene oxide, silver nanoparticle, drug delivery system, acetylsalicylic acid
  • 出版物名称:   NANOCOMPOSITES
  • ISSN:   2055-0324 EI 2055-0332
  • 通讯作者地址:  
  • 被引频次:   6
  • DOI:   10.1080/20550324.2022.2054210
  • 出版年:   2022

▎ 摘  要

Graphene has excellent properties which can be a promising material as nanocomposites for application in a drug delivery system (DDS). In this study, reduced graphene oxide/silver nanoparticles (rGO/AgNPs) nanocomposites was synthesized using a facile in-situ method for drug loading application of acetylsalicylic acid (ASA). The synthesis results were characterized by FESEM, EDX, UV-Vis, XRD, and Raman spectrophotometers analyses. The results showed that rGO/AgNPs nanocomposites was synthesized successfully. Drug loading application was performed using UV-Vis measurements. The loading results depicted that rGO/AgNPs is successfully created in high-capacity loading for ASA. Drug loading performances enhanced with the increasing loading time of ASA on rGO/AgNPs. The optimum percentage of drug loading capacity for ASA by rGO/AgNPs was similar to 83% in a contact time of 30 hrs. [GRAPHICS]