▎ 摘　　要

Doxorubicin (DOX) is an emerging environmental contaminant due to its significant genetic toxicity to mankind; hence, it is very important to remove them from aqueous media. In this paper, magnetic graphene oxide was modified/functionalized with different materials, i.e., l-phenyl alanine (PH) and polyethylene glycol (PEG), to be used as a new generation adsorbent for the removal of DOX. To do so, the effect of various factors (adsorbent dose, adsorbing time, solution pH, initial DOX concentration, and ultrasonic irradiation) on the amount of drug removal was evaluated by the Taguchi method. The results showed that among the different adsorbents, the PH-modified GO-Fe3O4 composite (GO-Fe3O4-PH) indicated a higher adsorption efficiency of about 99.3% at optimum conditions (initial concentration = 30 ppm, adsorbent = 8 mg, pH=6, and time = 5 min) under ultrasonic treatment (42 kHz). The adsorption manner of DOX was well described by the Langmuir-Freundlich, pseudo-second-order, and double exponential models with the 250.5 mg/g maximum capacity of the adsorbent. Moreover, the thermodynamic study indicates that the DOX adsorption process was exothermic and spontaneous. Remarkably, the desorption-recovery study indicated the successful reuse of the GO-Fe3O4-PH composite for the adsorption of DOX in six cycle runs without a significant loss in adsorption efficiency. Overall, the GO-Fe3O4-PH has the potential to be utilized as a promising adsorbent for the remediation of DOX-contaminated water, including short reaction time, environmentally benign, and operational simplicity features.