• 文献标题:   DNA analysis based on toehold-mediated strand displacement on graphene oxide
  • 文献类型:   Article
  • 作  者:   MIYAHATA T, KITAMURA Y, FUTAMURA A, MATSUURA H, HATAKEYAMA K, KOINUMA M, MATSUMOTO Y, IHARA T
  • 作者关键词:  
  • 出版物名称:   CHEMICAL COMMUNICATIONS
  • ISSN:   1359-7345 EI 1364-548X
  • 通讯作者地址:   Kumamoto Univ
  • 被引频次:   20
  • DOI:   10.1039/c3cc45531a
  • 出版年:   2013

▎ 摘  要

Fluorescent dye-labeled probe DNA was immobilized on fluorescence-quenching graphene oxide (GO) through a capture DNA. When targets were added, the probes were released from the GO through toehold-mediated strand exchange. Higher emission recovery and more signal contrast were achieved relative to conventional methods that are based on direct adsorption of probes.