• 文献标题:   Powerful antibacterial activity of graphene/nanoflower-like nickelous hydroxide nanocomposites
  • 文献类型:   Article
  • 作  者:   LI N, ZENG CJ, QIN QP, ZHANG BM, CHEN LN, LUO ZH
  • 作者关键词:   antibacterial activity, biocompatibility, longterm effectivenes, membrane, 3d gn/ni oh 2
  • 出版物名称:   NANOMEDICINE
  • ISSN:   1743-5889 EI 1748-6963
  • 通讯作者地址:   Yulin Normal Univ
  • 被引频次:   2
  • DOI:   10.2217/nnm-2018-0200
  • 出版年:   2018

▎ 摘  要

Aim: The development of new and efficient antibacterial agents is urgent to overcome emerging antimicrobial resistance. Materials & methods: Herein, we have presented a new type of 3D antibacterial system to prompt bacteria to contact with the any plane of nanocomposites. Results: Comparing the antibacterial activity of graphene oxide, reduced graphene oxide and graphene-loaded nanoflower-like nickelous hydroxide (GN/Ni(OH)(2)) nanocomposites; the GN/Ni(OH)(2) showed stronger bactericidal capability toward Gram-negative/-positive bacteria. Moreover, the GN/Ni(OH)(2) with low cytotoxicity can promote it as 'green' antimicrobial agents. And, the GN/Ni(OH)(2) presented long-term stable antibacterial effectiveness after 2-month storage. The antibacterial mechanisms of GN/Ni(OH)(2) were evidenced as the 3D contact and violent damage to the bacterial structure. Conclusion: The GN/Ni(OH)(2) provides new insights into the antibacterial properties of 3D nanocomposites for effectively fighting pathogen threats in biomedicine and public health.