• 文献标题:   Graphene quantum point contact transistor for DNA sensing
  • 文献类型:   Article
  • 作  者:   GIRDHAR A, SATHE C, SCHULTEN K, LEBURTON JP
  • 作者关键词:   solidstate membrane, transport, biomolecule, simulation
  • 出版物名称:   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
  • ISSN:   0027-8424
  • 通讯作者地址:   Univ Illinois
  • 被引频次:   53
  • DOI:   10.1073/pnas.1308885110
  • 出版年:   2013

▎ 摘  要

By using the nonequilibrium Green's function technique, we show that the shape of the edge, the carrier concentration, and the position and size of a nanopore in graphene nanoribbons can strongly affect its electronic conductance as well as its sensitivity to external charges. This technique, combined with a self-consistent Poisson-Boltzmann formalism to account for ion charge screening in solution, is able to detect the rotational and positional conformation of a DNA strand inside the nanopore. In particular, we show that a graphene membrane with quantum point contact geometry exhibits greater electrical sensitivity than a uniform armchair geometry provided that the carrier concentration is tuned to enhance charge detection. We propose a membrane design that contains an electrical gate in a configuration similar to a field-effect transistor for a graphene-based DNA sensing device.