• 文献标题:   Simultaneous Determination of Adenine and Guanine Using Cadmium Selenide Quantum Dots-Graphene Oxide Nanocomposite Modified Electrode
  • 文献类型:   Article
  • 作  者:   KALAIVANI A, NARAYANAN SS
  • 作者关键词:   adenine, guanine, cdse quantum dot, graphene oxide, herring sperm dna
  • 出版物名称:   JOURNAL OF NANOSCIENCE NANOTECHNOLOGY
  • ISSN:   1533-4880 EI 1533-4899
  • 通讯作者地址:   Univ Madras
  • 被引频次:   8
  • DOI:   10.1166/jnn.2015.9717
  • 出版年:   2015

▎ 摘  要

A novel electrochemical sensor was fabricated by immobilizing Cadmium Selenide Quantum Dots (CdSe QDs)-Graphene Oxide (GO) nanocomposite on a paraffin wax impregnated graphite electrode (PIGE) and was used for the simultaneous determination of adenine and guanine. The CdSe QDs-GO nanocomposite was prepared by ultrasonication and was characterized with spectroscopic and microscopic techniques. The nanocomposite modified electrode was characterized by cyclic voltannmetry (CV). The modified electrode showed excellent electrocatalytic activity towards the oxidative determination of adenine and guanine with a good peak separation of 0.31 V. This may be due to the high surface area and fast electron transfer kinetics of the nanoconnposite. The modified electrode exhibited wide linear ranges from 0.167 mu M to 245 mu M for Guanine and 0.083 mu M to 291 mu M for Adenine with detection limits of 0.055 mu M Guanine and 0.028 mu M of Adenine (S/N = 3) respectively. Further, the modified electrode was used for the quantitative determination of adenine and guanine in herring sperm DNA with satisfactory results. The modified electrode showed acceptable selectivity, reproducibility and stability under optimal conditions.