▎ 摘　　要

The present work reports a possibility of using a layer made of graphene supporting platinum nanoparticles (PtNPs-GR) in electrochemical sensors as active and intermediate layer. New sensors with greatly improved both potentiometric and voltammetric signals were prepared by using a simple and effective drop casting method and characterized by a cyclic voltammetry and a electrochemical impedance spectroscopy. The performance of the new potentiometric sensor was evaluated by the use an ion-selective membrane with well-known valinomycin ion carrier. Potassium electrodes had a Nernstian slope (59.10 mV/pK), high stability and reproducibility of the standard potential values, and a very small drift potential. Under optimized operating conditions, the voltammetric sensor with PtNPs-GR responded to paracetamol concentration in the range from 20 nM to 2.2 mu M with the detection limit of 8 nM.