• 文献标题:   Starch-borate-graphene oxide nanocomposites as highly efficient targeted antitumor drugs
  • 文献类型:   Article
  • 作  者:   CHENG RM, OU SJ, BU YX, LI X, LIU XH, WANG YQ, GUO R, SHI BY, JIN DY, LIU Y
  • 作者关键词:  
  • 出版物名称:   RSC ADVANCES
  • ISSN:   2046-2069
  • 通讯作者地址:   Wenzhou Med Univ
  • 被引频次:   2
  • DOI:   10.1039/c5ra17622k
  • 出版年:   2015

▎ 摘  要

We synthesized novel borate antitumor drugs sourced from starch-borate-graphene oxide (SBG) nanocomposites. In vitro results suggest that SBG from the molar ratio of n(starch) : n(borate) : n(GO) at 2 : 1 : 1 exhibits excellent biocompatibility with normal human cells (> 90% cell viability), but are highly toxic against cancer cells (<20% cell viability).