▎ 摘　　要

A graphene modified glassy carbon electrode was fabricated for sensitive and convenient electrochemical detection of 1-hydroxypyrene (1-OHP). The graphene modified electrode was prepared by eletrochemical reduction of graphene oxide on glass carbon electrode. 1-OHP was synergistically accumulated on the graphene modified electrode via Tt-a conjugate adsorption and electrochemical oxidation. Electrochemical behavior of OHP on the graphene modified glass carbon electrode was studied in detail. The developed method gave a linear calibration curve for the determination of 1-OHP in the range of 5-300 nM (R-2 = 0.997), a limit of detection of 0.84 nM (S/N = 3). The proposed method was also successfully applied to the analysis of urine samples for OHP with the recoveries of 97.3-101.1%.