▎ 摘　　要

A facile one-step route was presented to prepared NH2-MIL-88B(Fe) and Fe3O4 modified reduced graphene oxide nanoparticles (NH2-MIL-88B(Fe)@MRGO) as mimic enzymes. The as-prepared NH2-MIL-88B(Fe)@MRGO exhibits a higher affinity for hydrogen peroxide and thus possessed a prominent peroxidase-mimic activity. Under the most favorable conditions, the hybrid nanomaterials with high catalytic velocity (2.57 x 10(-7) M s(-1)) and affinity (Km = 0.0091 mM) for substrates of H2O2 display a great glucose detection performance in the range of 20-800 mu M with a Limit of detection (LOD) of 3.16 mu M (S/N = 3). Graphic Abstract Favorable mimic enzymes catalysis is achieved on NH2-MIL-88B(Fe) and Fe3O4 modified reduced graphene oxide nanoparticles (NH2-MIL-88B(Fe)@MRGO) for glucose detection. [GRAPHICS]