• 文献标题:   DMF-exfoliated graphene for electrochemical NADH detection
  • 文献类型:   Article
  • 作  者:   KEELEY GP, O NEILL A, HOLZINGER M, COSNIER S, COLEMAN JN, DUESBERG GS
  • 作者关键词:  
  • 出版物名称:   PHYSICAL CHEMISTRY CHEMICAL PHYSICS
  • ISSN:   1463-9076
  • 通讯作者地址:   Univ Grenoble 1
  • 被引频次:   58
  • DOI:   10.1039/c1cp20060g
  • 出版年:   2011

▎ 摘  要

The electrochemical detection of NADH is of considerable interest because it is required as a cofactor in a large number of dehydrogenase-based biosensors. However, the presence of oxygenated functionalities on the electrode often causes fouling due to the adsorption of the oxidised form, NAD(+). Here we report an electroanalytical NADH sensor based on DMF-exfoliated graphene. The latter is shown to have a very low oxygen content, facilitating the exceptionally stable and sensitive detection of this important analyte.